HPLC Column, HPS Silica, 5um, 2.1mm ID x 50mm Length, 120A. Cogent Brand. 1 EA.
Additional Info:
75001-05P-2 Cogent HPS Silica™ HPLC Column is built with a high‑purity, unmodified silica stationary phase, providing reliable and reproducible performance for normal phase chromatography and USP L3 methods.
Unlike bonded phases, HPS Silica™ is chemically unmodified, allowing strong interactions with polar and hydrophilic compounds, making it ideal for lipid, fat, and other normal phase separations.
This proprietary silica has been widely used in HPLC laboratories for years, offering consistent performance and serving as a dependable alternative to commonly used silica columns such as Inertsil® and Luna®.
The 5 µm particle size provides a balance of efficiency and durability, allowing operation at higher flow rates with lower backpressure, making it well‑suited for routine analytical methods.
50 mm Length – Fast Normal Phase Separations
The 50 mm column length is optimized for speed and efficiency.
Short run times for rapid analysis
Reduced solvent consumption
Ideal for method development and screening
✅ Recommended for fast normal phase HPLC and high‑throughput workflows
2.1 mm ID – Low Flow Analytical Format
Designed for 2.1 mm ID analytical columns
Reduces solvent consumption
Ideal for LC‑MS compatible workflows
Maintains sensitivity in low‑flow systems
✅ Recommended for labs seeking solvent savings and efficient separations
Flow Rate & System Requirements (2.1 mm ID, 5 µm)
⚠️ Requires low‑flow capable HPLC or UHPLC system
Typical flow rate range: ~0.2 – 0.4 mL/min
Lower backpressure compared to smaller particle columns
Suitable for standard HPLC systems with low‑flow capability
Compatible with UV and MS detection
✅ Important: Ensure system can deliver stable low‑flow performance
Why Choose HPS Silica™ Columns
High‑Purity Unmodified Silica
Ideal for normal phase chromatography
Strong interaction with polar compounds
USP L3 Compatibility
Suitable for regulated and compendial methods
Reliable alternative to other silica columns
Reproducible Performance
Consistent selectivity across batches
Proven reliability in long‑term use
Performance Advantages
Lower Backpressure (5 µm Particles)
Enables higher flow rates
Compatible with standard HPLC systems
Fast Equilibration
Reduces time between runs
Excellent for Polar Compounds
Strong retention in normal phase mode
Ideal for lipids and hydrophilic analytes
Typical Applications
Fats and lipid analysis
Normal phase HPLC methods
Polar compound separations
USP L3 method compliance
Food, pharmaceutical, and chemical analysis
Important Usage Notes
Designed for normal phase chromatography conditions
Use appropriate non‑polar mobile phases
Requires proper solvent preparation and system equilibration
Store and handle using standard silica column protocols